Work at UNL

48. Roman-Arocho, G. M.; Shang, X.; Niu, W.; Guo, J.*  “Design of fluorescent protein-based sensors through a general protection−deprotection strategy”  Methods Enzymol. 2020, 640, 63-82.

47. Niu, W.*; Willett, H.; Mueller, J.; He, X.; Ma, B.; Guo, J. “Direct biosynthesis of adipic acid from lignin-derived aromatics using engineered Pseudomonas putida KT2440” Metab. Eng. 202059, 151-161.

46. Kramer, L.; Le X.; Hankore, E. D.; Wilson, M. A., Guo, J.; Niu, W.  “Engineering and characterization of hybrid carboxylic acid reductases”  J. Biotechnol. 2019, 304, 52-56.

45. Cao, Y.; Zhang, R.; Liu, W.; Zhao, G.; Niu, W.; Guo, J.; Xian, M.; Liu, H. “Manipulation of the precursor supply for high-level production of longifolene by metabolically engineered Escherichia coli”  Sci. Rep. 2019, 9:95.

44. Hankore, E.; Zhang, L.; Chen, Y.; Liu, K.; Niu, W.; Guo, J.* “Genetic incorporation of noncanonical amino acids using two mutually orthogonal quadruplet codons”  ACS Synth. Biol. 2019, 8, 1168-1174.

43. Lawrie, J.; Niu, W.;* Guo, J.* “Engineering of a sulfotyrosine-recognizing small protein scaffold for the study of protein tyrosine O-sulfation”  Methods Enzymol. 2019, 622, 67-89.

42. Niu, W.; Kramer, L.; Mueller, J.; Liu, K.; Guo, J. “Metabolic engineering of Escherichia coli for the de novo stereospecific biosynthesis of 1,2-propanediol through lactic acid”  Metab. Eng. Commun. 2018, 8:e00082.

41. Liu, Y.; He, X.; Lim, W.; Mueller, J.; Lawrie, J.; Kramer, L.; Guo, J.; Niu, W. “Deciphering molecular details in the assembly of alpha-type carboxysome” Sci. Rep. 2018, 8, 15062.

40. Chen, Y.; Wan, Y.; Wang, N.; Yuan, Z.; Niu, W.*; Li, Q.*; Guo, J.* “Controlling the Replication of a Genomically Recoded HIV1 with a Functional Quadruplet Codon in Mammalian Cells”  ACS Synth. Biol. 2018, 7, 1612-1617.

39. Kramer, L.; Hankore, E. D.; Liu, Y.; Liu, K.; Jimenez, E.; Guo, J.* Niu, W.*  “Characterization of Carboxylic Acid Reductases for Biocatalytic Synthesis of Industrial Chemicals” ChemBioChem, 2018, 19, 1452-1460.

38. Shang, X.; Chen, Y.; Wang, N.; Niu, W.; Guo, J.* “Oxidation-induced generation of a mild electrophile for proximity-enhanced protein–protein crosslinking” Chem. Commun. 2018, 54, 4172 – 4175.

37. Lawrie, J.; Song, X.; Niu, W.*; Guo, J.* “A high throughput approach for the generation of orthogonally interacting protein pairs” Sci. Rep. 2018, 8, 867.

36. Shang, X., Lai, R.; Song, X.; Li, H.; Niu, W.; Guo, J.*  “Improved Photoinduced Fluorogenic Alkene−Tetrazole Reaction for Protein Labeling” Bioconjug. Chem. 2017, 28, 2859-2864

35. Liu, K.; Enns, B.; Evans, B.; Wang, N.; Shang, X.; Sittiwong, W.; Dussault, P.;* Guo, J.* “A Genetically Encoded Cyclobutene Probe for Labeling of Live Cells” Chem. Commun. 2017, 53, 10604-10607.

34. Shang, X.; Wang, N.; Cerny, R.; Niu, W.; Guo, J*.  “Fluorescent Protein-Based Turn-On Probe Through A General Protection-Deprotection Design Strategy” ACS Sens. 2017, 2,961–966.

33. Niu, W.*; Guo, J.* “Novel fluorescence-based biosensors incorporating unnatural amino acids” Methods Enzymol. 2017, 589, 191-219.

32. Yuan, Z.; Wang, N.; Kang, G.; Niu, W.*; Li, Q.*; Guo, J.*  “Controlling multi-cycle replication of live-attenuated HIV-1 using an unnatural genetic switch” ACS Synth. Biol. 2017, 6, 721–731.

31. Shang, X.; Song, X.; Faller, C.; Lai, R.; Li, H.; Cerny, R.; Niu, W.*; Guo, J.*  “Fluorogenic Protein Labeling Using A Genetically Encoded Unstrained Alkene”  Chem. Sci. 2017, 8, 1141-1145.

30. Wang, N.; Yuan, Z.; Niu, W.*; Li, Q.*; Guo, J.* “Synthetic biology approach for the development of conditionally replicating HIV-1 vaccine” J. Chem. Technol. Biotechnol. 2016, DOI 10.1002/jctb.5174 (invited review)

29. Niu, W.; Guo, J.; Van Dien, S.  “Heterologous Pathway Engineering” in Metabolic Engineering for Bioprocess Commercialization 2016, 31-52.

28. Ju, T.; Hu, J.; Xiang, S. H.*; Guo, J.* “Sulfotyrosine dipeptide: Synthesis and evaluation as HIV-entry inhibitor”  Bioorg. Chem. 2016, doi: 10.1016/j.bioorg.2016.07.012.

27. Ju, T.; Niu, W.*; Guo, J.* “Evolution of SH2 Domain to Recognize Sulfotyrosine” ACS Chem. Biol. 2016, DOI: 10.1021/acschembio.6b00555.

26. Grady, G.; Thelen, A.; Albers, J.; Ju, T.; Guo, J.; Barycki, J. J.; Simpson, M. A.  “Inhibiting Hexamer Disassembly of Human UDP-Glucose Dehydrogenase by Photoactivated Amino Acid Cross-Linking”  Biochemistry 2016, 55, 3157–3164.

25. Song, X., Shang, X.; Ju, T.; Niu, W.*, Guo, J.* “A Photoactivable Src Homology 2 (SH2) Domain” RCS Advances 2016, 6, 51120-51124.

24. Liu, W.; Xu, X.; Zhang, R.; Cheng, T.; Cao, Y.; Li, X.; Guo, J.; Liu, H.; Xian, M. “Engineering Escherichia coli for high-yield geraniol production with biotransformation of geranyl acetate to geraniol under fed-batch culture” Biotechnol. Biofuels. 2016, 9:58.

23. Cao, Y.; Cheng, T.; Zhao, G.; Niu, W.; Guo, J.; Xian, M.; Liu, H. “Metabolic engineering of Escherichia coli for the production of hydroxy fatty acids from glucose” BMC Biotechnol. 2016, 16:26.

22. Wang, N.; Shang, X.; Cerny, R.; Niu, W.*; Guo, J.* “Systematic Evolution and Study of UAGN Decoding tRNAs in a Genomically Recoded Bacteria.” Sci. Rep. 2016, 6, 21898.

21. Tong, W.; Xu, Y.; Xian, M.; Niu, W.; Guo, J.; Liu, H.; Zhao, G. “Biosynthetic pathway for acrylic acid from glycerol in recombinant Escherichia coliAppl. Microbiol. Biotechnol. 2016, 100, 4901-4907.

20.Cao, Y.; Niu, W.; Guo, J.; Xian, M.; Liu, H.Biotechnological production of 1,2,4-butanetriol: An efficient process to synthesize energetic material precursor from renewable biomass.” Sci. Rep. 2015, 5, 18149.

19. Niu, W.*; Guo, J.* “Stereospecific Microbial Conversion of Lactic Acid into 1,2-Propanediol” ACS Synth. Biol. 2015, 4, 378-382.

18. Wang, N.; Ju, T.; Niu, W.; Guo, J.* “Fine-tuning Interaction between Aminoacyl-tRNA Synthetase and tRNA for Efficient Synthesis of Proteins Containing Unnatural Amino Acids” ACS Synth. Biol. 2015, 4, 207-212.

17. Wang, N.; Li, Y.; Niu, W.; Sun, M.; Cerny, R.; Li, Q.;* Guo, J.* “Construction of a Live-Attenuated HIV-1 Vaccine through Genetic Code Expansion” Angew. Chem. Int. Ed. 2014, 126, 4967-4971. ( This article was highlighted in Nature Chemistry.)

16. Niu, W.; Guo, J.* “Expanding the Chemistry of Fluorescent Protein Biosensors by Genetic Incorporation of Unnatural Amino Acids” Mol. Biosyst. 2013, 9, 2961-2970. (the second most read article in October, 2013)

15. Wang, G.; Xu, Z.; Chen, Z.; Niu, W.; Zhou, Y.; Guo, J.; Tan, L. “Sequential binding of large molecules to hairy MOFs” Chem. Commun. 2013, 49, 6641-6643.

14. Ju, T.; Niu, W.; Ronald Cerny; Bollman, J.; Roy, A. Guo, J.* “Molecular Recognition of Sulfotyrosine and Phosphotyrosine” Mol. Biosyst. 2013, 9, 1829 – 1832.

13. Niu, W.; Schultz, P. G.; Guo, J.* “An Expanded Genetic Code In Mammalian Cells With a Functional Quadruplet Codon” ACS Chem. Biol. 2013, 8, 1640-1645. (the second most read article in May, 2013; podcast interview with the journal)

12. Wang, F.; Niu, W.; Guo, J.*; Schultz, P. G.* “Unnatural Amino Acid Mutagenesis of Fluorescent Proteins” Angew. Chem. Int. Ed. 2012, 51, 10132-10135.

11. Park, C. M.; Niu, W.; Liu, C.; Biggs, T. D.; Guo, J.; Xian, M.* “A Proline-Based Phosphine Template for Staudinger Ligation” Org. Lett. 2012, 14, 4694-4697.

Work prior to UNL

10. Chatterjee, A.; Guo, J.; Lee, H. S.; Schultz, P. G. “A Genetically Encoded Fluorescent Probe in Mammalian Cells” J. Am. Chem. Soc. 2013, 135, 12540–12543.

9. Wang, F.; Robbins, S.; Guo, J.; Shen, W.; Schultz, P. G. “Genetic Incorporation of Unnatural Amino Acid into Proteins in Mycobacterium tuberculosis” PloS One 2010, 5, e9354.

8. Guo, J.; Melançon III, C. E.; Lee, H. S.; Groff, D.; Schultz, P. G. "Evolution of Amber Suppressor tRNAs for Efficient Bacterial Production of Unnatural Amino Acid-Containing Proteins" Angew. Chem. Int. Ed. Engl. 2009, 48, 9148-9151.

7. Lee, H.S.; Guo, J.; Lemke, E. A.; Dimla, R. D.; Schultz, P. G. "The Genetic Incorporation of a Small, Environmentally Sensitive, Fluorescent Probe into Proteins in S. cerevisiae" J. Am. Chem. Soc. 2009, 131, 12921-12923.

6. Chen, P.; Groff, D.; Guo, J., Ou, W.; Cellitti, S.; Geierstanger, B. H.; Schultz, P. G. "A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells" Angew. Chem. Int. Ed. Engl. 2009, 48, 4052-4055. (This article was selected as "Hot Papers" in Angew. Chem. Int. Ed.)

5. Guo, J.; Wang, J.; Lee, J. S.; Schultz, P. G. “Site-Specific Incorporation of Methyl- and Acetyl- Lysine Analogues into Recombinant Proteins” Angew. Chem. Int. Ed. 2008, 47, 6399-6401. (This article was highlighted in “Faculty of 1000 Biology”.

4. Guo, J.; Wang, J.; Anderson, J. C.; Schultz, P. G. “Addition of an α-Hydroxy Acid to the Genetic Code of Bacteria” Angew. Chem. Int. Ed. 2008, 47, 722-725. (This article was highlighted in Nature.)

3. Guo, J.; Frost, J. W. “Synthesis of 5-Amino-5-deoxyshikimate” Org. Lett. 2004, 6, 1585-1588. (This article was highlighted in Nat. Prod. Rep.)

2. Guo, J.; Frost, J. W. “Kanosamine Biosynthesis: A Likely Source of the Aminoshikimate Pathway's Nitrogen Atom” J. Am. Chem. Soc. 2002, 124, 10642-10643.

1. Guo, J.; Frost, J. W. “Biosynthesis of 1-Deoxy-1-imino-D-erythrose 4-phosphate: A Defining Metabolite in the Aminoshikimate Pathway” J. Am. Chem. Soc. 2002, 124, 528-529.



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