{"id":6,"date":"2014-02-17T19:37:32","date_gmt":"2014-02-17T19:37:32","guid":{"rendered":"http:\/\/chemweb.unl.edu\/ldu\/?page_id=6"},"modified":"2022-04-21T18:07:01","modified_gmt":"2022-04-21T23:07:01","slug":"du-group-home","status":"publish","type":"page","link":"http:\/\/chemweb.unl.edu\/ldu\/du-group-home\/","title":{"rendered":"Du Group Home"},"content":{"rendered":"<p>Welcome to the homepage for the Du Group at the University of Nebraska-Lincoln. Our research deals with the biosynthesis of natural products. We are particularly interested in those structurally complex, biologically active compounds produced by fungi and bacteria. The studies are at the interface of chemistry and biology, including cloning biosynthetic genes, expressing the genes in heterologous hosts, purifying enzymes and characterizing their activities, metabolic engineering through mutagenesis, recombination and fermentation, and isolation and structural determination of metabolites.<\/p>\n<p>Work highlighted on JACS website <a href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ja8091054\" target=\"_blank\" rel=\"noopener noreferrer\">more&#8230;<\/a><\/p>\n<p><a title=\"Group News\" href=\"http:\/\/chemweb.unl.edu\/ldu\/?page_id=51\">Read more group news!<\/a><\/p>\n<p><center><div id=\"metaslider-id-1152\" style=\"width: 100%;\" class=\"ml-slider-3-20-3 metaslider metaslider-flex metaslider-1152 ml-slider\">\n    <div id=\"metaslider_container_1152\">\n        <div id=\"metaslider_1152\">\n            <ul aria-live=\"polite\" class=\"slides\">\n                <li style=\"display: block; width: 100%;\" class=\"slide-1153 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide1-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Drug Discovery from Underexplored Microorganisms\" class=\"slider-1152 slide-1153\" title=\"Drug Discovery from Underexplored Microorganisms\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1154 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide2-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Identification of Natural Antibiotics\" class=\"slider-1152 slide-1154\" title=\"Identification of Natural Antibiotics\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1155 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide3-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Biosynthetic Pathway\" class=\"slider-1152 slide-1155\" title=\"Biosynthetic Pathway\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1156 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide4-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Molecular Mechanism for Biosynthesis\" class=\"slider-1152 slide-1156\" title=\"Molecular Mechanism for Biosynthesis\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1157 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide5-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Molecular Mechanism and One-Pot Biosynthesis\" class=\"slider-1152 slide-1157\" title=\"Molecular Mechanism and One-Pot Biosynthesis\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1158 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide6-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Synthetic Biology: Yield Improvement\" class=\"slider-1152 slide-1158\" title=\"Synthetic Biology: Yield Improvement\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1159 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide7-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Synthetic Biology: Activation of Cryptic Gene Cluster\" class=\"slider-1152 slide-1159\" title=\"Synthetic Biology: Activation of Cryptic Gene Cluster\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1160 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide8-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Regulation of Biosynthesis\" class=\"slider-1152 slide-1160\" title=\"Regulation of Biosynthesis\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1161 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide9-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Regulation of Intrinsic Antibiotic Resistance\" class=\"slider-1152 slide-1161\" title=\"Regulation of Intrinsic Antibiotic Resistance\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1162 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/slide10_2-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Function in Biology: HSAF-Fe Complexes\" class=\"slider-1152 slide-1162\" title=\"Function in Biology: HSAF-Fe Complexes\" \/><\/li>\n                <li style=\"display: none; width: 100%;\" class=\"slide-1163 ms-image\"><img src=\"http:\/\/chemweb.unl.edu\/ldu\/wp-content\/uploads\/2014\/02\/Slide11-640x360.jpg\" height=\"360\" width=\"640\" alt=\"Function in Biology: Predator-Prey Interactions\" class=\"slider-1152 slide-1163\" title=\"Function in Biology: Predator-Prey Interactions\" \/><\/li>\n            <\/ul>\n        <\/div>\n        \n    <\/div>\n<\/div><\/center><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Welcome to the homepage for the Du Group at the University of Nebraska-Lincoln. Our research deals with the biosynthesis of natural products. We are particularly interested in those structurally complex, biologically active compounds produced by fungi and bacteria. The studies are at the interface of chemistry and biology, including cloning biosynthetic genes, expressing the genes<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":[],"guten_post_layout_featured_media_urls":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"guten_post_layout_landscape_large":false,"guten_post_layout_portrait_large":false,"guten_post_layout_square_large":false,"guten_post_layout_landscape":false,"guten_post_layout_portrait":false,"guten_post_layout_square":false,"featured_image":false,"frontpage_image":false,"custom_header_image":false},"_links":{"self":[{"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/pages\/6"}],"collection":[{"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/comments?post=6"}],"version-history":[{"count":10,"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/pages\/6\/revisions"}],"predecessor-version":[{"id":1252,"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/pages\/6\/revisions\/1252"}],"wp:attachment":[{"href":"http:\/\/chemweb.unl.edu\/ldu\/wp-json\/wp\/v2\/media?parent=6"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}